To build a prediction for the Istiqlol Dushanbe - Khatlon match, scheduled for 14 July 2021, several key factors could influence the outcome. Istiqlol Dushanbe have played 48 matches, in which they won 35 of them, drew 9 times and lost 4 matches. Khatlon, having played 50 matches, won 15 times, drew 19 matches and lost 16 defeats. In the league, Istiqlol Dushanbe average 2.9 goals scored per game and 0.8 conceded. Khatlon average 1.3 scored and 1.3 conceded. These sides last met on 19 February 2021 at Khatlon's ground, where the away side proved stronger.